Flavonoids

Updated: Apr 5, 2019


Flavonoids are among the most diverse group of plant chemicals throughout nature, with over 5000 different flavonoids being identified. They are the key to colours in our fruits and act as a plants defender against pesky pests. Within the expanding world of cannabis, these phenolic compounds has been identified to have an impact through a diverse spectrum of functions.

There are over 20 flavonoids in cannabis found throughout the flowers, leaves, and stems; estimated at 2.5% its dry weight. Contributing to a wide range of effects, it can effect physical changes such as:

  • smell and flavour of a cannabis strain,

  • pigmentation on cannabis flowers,

  • thwart unwanted pests while growing;

or it can also offer pharmacological effects such as:

  • moderating side effects of THC,

  • influencing the entourage effect,

  • increase metabolism of other cannabinoids and chemicals,

  • anti-inflammatory, anti-fungal, antioxidant,

  • regenerative and neuro-protective properties.

Flavonoids share similar characteristics with terpenes and cannabinoids. They can also be effectively ingested by smoking, or preferably vaporizing, plant material.

Key Flavonoids


Cannaflaviin:

  • Shown strong anti-inflammatory characteristics with a potential to be more potent than aspirin for relief. Further research is currently being focused on B and C.

  • Extraction Temperature: 180 °C / 360 °F





Beta-sitosterol

  • In use to make medicine for heart disease and high cholesterol.

  • Extraction Temperature: 133 °C / 273 °F



Apigenin


  • Shown to help the body modulates responses to drugs, crossing the blood-brain barrier, regenerative properties and suggestion of effect on the endocannabinoid system.

  • Extraction Temperature: 177 °C / 352 °F



Orientin

  • Found in the passion flower, the Açaí palm, buckwheat sprouts, millets; showing promising effects in the following areas: antioxidant, anti-aging, antiviral, anti-inflammation, vasodilatation and cardioprotective, radioprotective, neuroprotective, anti-adipogenesis, and antinociceptive effects.



Quercetin

  • Antioxidant and anti-inflammatory effects, can help reduce inflammation, kill cancer cells, control blood sugar, and help prevent heart disease.

  • Extraction Temperature: 250 °C / 482 °F


Kaempferol

  • Augments the body’s antioxidant defense against free radicals and reported to modulate a number of key elements in the death of cells, formation of new blood vessels, inflammation, among more.

  • Extraction Temperature: 277 °C / 530 °F

Two more notorious flavonoids are the key actors in creating the variation of purple hues found in cannabis:


Anthoxanthins

Appears as white or colorless to a creamy to yellow, often on petals of flowers. Also exhibits antioxidant properties.



Anthocyanins

Appears as red, purple or blue pigmentation found in blueberries, raspberries and black rice among many others. It is seen to have an effect to facilitate interactions with other chemicals in the body.

Among better understanding the full spectrum of the cannabis plant, research has continued on phenolic amides and lignanamides belonging to the lignan class of compounds, common in flax seeds and sesame seeds, which can improve digestive health, lower blood pressure and bad cholesterol.

Lignanamides unique to cannabis include:


Cannabisin

  • existing in these types of compounds: A-, B-, C-, D-, E-, F-,

  • Cannabisin B has shown to have positive effects in initiating cell regeneration to combat diseases.







Here are strains that exhibit properties of flavonoids:

Sativa - San Rafael - Tangerine Dream










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